Dielectrophoretic cell trapping and parallel one-to-one fusion based on field constriction created by a micro-orifice array
نویسندگان
چکیده
منابع مشابه
A microfabricated dielectrophoretic trapping array for cell-based biological assays
This thesis presents the development of a small planar array of microfabricated traps for holding single cells and performing assays on them. The traps use the phenomenon of dielectrophoresis—the force on polarizable bodies in a non-uniform electric field—to make potential energy wells. These potential energy wells are electrically switchable, arrayable, and amenable to batch fabrication. The t...
متن کاملA Scalable Row/column-addressable Dielectrophoretic Cell-trapping Array
We present the first known implementation of a passive, scalable architecture for trapping, imaging, and sorting individual cells using a positive dielectrophoretic (p-DEP) trapping array. Our approach, which does not require on-chip CMOS electronics, incorporates unique “ring-dot” p-DEP trap geometries into an “active coverslip” array, enabling selection of individual cells from a trapped popu...
متن کاملSorting by Parallel Insertion on a One-Dimensional Subbus Array
We consider the problem of sorting on a one-dimensional sub-bus array of processors. The sub-bus broadcast operation makes possible a new class of parallel sorting algorithms whose complexity we analyze with the parallel insertion model. A sorting method, or sorting strategy, in the parallel insertion model, uses a sequence of left and right insertion steps, of which we give two types: greedy i...
متن کاملCell separation by dielectrophoretic field-flow-fractionation.
Dielectrophoretic field-flow-fractionation (DEP-FFF) was applied to several clinically relevant cell separation problems, including the purging of human breast cancer cells from normal T-lymphocytes and from CD34+ hematopoietic stem cells, the separation of the major leukocyte subpopulations, and the enrichment of leukocytes from blood. Cell separations were achieved in a thin chamber equipped ...
متن کاملDesign and Simulation of a Fluidic Micro-Bio-Sensor Based on Resonator Array
In this paper, a fluidic biosensor with possibility to fabricate by Micro-Electro-Mechanical Systems (MEMS) technology is proposed for biomedical mass detection and lab-on-chip applications. This is designed by electromechanical coupling of harmonic micromechanical resonators with harmonic springers as a mechanical resonator array. It can disperse mechanical wave along the array by electrostati...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomicrofluidics
سال: 2010
ISSN: 1932-1058
DOI: 10.1063/1.3422544